ScoA

• Description: probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
  
  

Gene name	scoA
Synonyms	yxjD
Essential	no
Product	probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Function	lipid metabolism
MW, pI	25 kDa, 6.613
Gene length, protein length	714 bp, 238 aa
Immediate neighbours	scoB, yxjC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of lipids, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, SigE regulon

The gene

Basic information

• Locus tag: BSU38990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA (according to Swiss-Prot)

• Protein family: 3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)

• Paralogous protein(s): YodS

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3CDK

• UniProt: P42315

• KEGG entry: [3]

• E.C. number: 2.8.3.5

Expression and regulation

• Operon: yxjC-scoA-scoB-yxjF PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: