CotS

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  • Description: spore coat protein

Gene name cotS
Synonyms
Essential no
Product spore coat protein
Function resistance of the spore
MW, pI 40 kDa, 6.641
Gene length, protein length 1053 bp, 351 aa
Immediate neighbours ytxO, cotSA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU30900

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cotS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Ritsuko Kuwana, Hiromi Ikejiri, Satoko Yamamura, Hiromu Takamatsu, Kazuhito Watabe
Functional relationship between SpoVIF and GerE in gene regulation during sporulation of Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 1);163-170
[PubMed:14702409] [WorldCat.org] [DOI] (P p)

S Little, A Driks
Functional analysis of the Bacillus subtilis morphogenetic spore coat protein CotE.
Mol Microbiol: 2001, 42(4);1107-20
[PubMed:11737650] [WorldCat.org] [DOI] (P p)

H Takamatsu, T Kodama, K Watabe
Assembly of the CotSA coat protein into spores requires CotS in Bacillus subtilis.
FEMS Microbiol Lett: 1999, 174(1);201-6
[PubMed:10234840] [WorldCat.org] [DOI] (P p)

H Takamatsu, Y Chikahiro, T Kodama, H Koide, S Kozuka, K Tochikubo, K Watabe
A spore coat protein, CotS, of Bacillus subtilis is synthesized under the regulation of sigmaK and GerE during development and is located in the inner coat layer of spores.
J Bacteriol: 1998, 180(11);2968-74
[PubMed:9603889] [WorldCat.org] [DOI] (P p)

Akiko Abe, Hidekatsu Koide, Takeyuki Kohno, Kazuhito Watabe
A Bacillus subtilis spore coat polypeptide gene, cotS.
Microbiology (Reading): 1995, 141 ( Pt 6);1433-1442
[PubMed:7545510] [WorldCat.org] [DOI] (P p)