TcyL

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Gene name tcyL
Synonyms ytmL
Essential no
Product cystine ABC transporter (permease)
Function cystine uptake
Interactions involving this protein in SubtInteract: TcyL
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 26 kDa, 9.3
Gene length, protein length 717 bp, 239 aa
Immediate neighbours tcyM, tcyK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtmL context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

CymR regulon, YtlI regulon

The gene

Basic information

  • Locus tag: BSU29360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: binding-protein-dependent transport system permease family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed