ResD

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  • Description: two-component response regulator, regulation of aerobic and anaerobic respiration

Gene name resD
Synonyms ypxD
Essential no
Product two-component response regulator
Function regulation of aerobic and anaerobic respiration
respiration
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation), Central C-metabolism, Stress, Alternative nitrogen sources
MW, pI 27 kDa, 5.631
Gene length, protein length 720 bp, 240 aa
Immediate neighbours resE, resC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ResD context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

regulators of electron transport, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, ResD regulon

The ResD regulon

The gene

Basic information

  • Locus tag: BSU23120

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by ResE on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
    • repressed by glucose (CcpA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References