BltD
- Description: spermidine/ spermine acetyltransferase
Gene name | bltD |
Synonyms | bmr2D, bmtD |
Essential | no |
Product | spermidine/ spermine acetyltransferase |
Function | spermidine degradation |
MW, pI | 17 kDa, 6.087 |
Gene length, protein length | 456 bp, 152 aa |
Immediate neighbours | blt, yrkA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU26600
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39909
- KEGG entry: [3]
- E.C. number: 2.3.1.57
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
D P Woolridge, J D Martinez, D E Stringer, E W Gerner
Characterization of a novel spermidine/spermine acetyltransferase, BltD, from Bacillus subtilis.
Biochem J: 1999, 340 ( Pt 3)(Pt 3);753-8
[PubMed:10359661]
[WorldCat.org]
(P p)
N N Baranova, A Danchin, A A Neyfakh
Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters.
Mol Microbiol: 1999, 31(5);1549-59
[PubMed:10200972]
[WorldCat.org]
[DOI]
(P p)
D P Woolridge, N Vazquez-Laslop, P N Markham, M S Chevalier, E W Gerner, A A Neyfakh
Efflux of the natural polyamine spermidine facilitated by the Bacillus subtilis multidrug transporter Blt.
J Biol Chem: 1997, 272(14);8864-6
[PubMed:9083003]
[WorldCat.org]
[DOI]
(P p)
M Ahmed, L Lyass, P N Markham, S S Taylor, N Vázquez-Laslop, A A Neyfakh
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.
J Bacteriol: 1995, 177(14);3904-10
[PubMed:7608059]
[WorldCat.org]
[DOI]
(P p)