NicK
- Description: DNA relaxase, similar to transposon protein
| Gene name | nicK |
| Synonyms | ydcR |
| Essential | no |
| Product | DNA relaxase, similar to transposon protein |
| Function | conjugation of ICE BS1 |
| MW, pI | 40 kDa, 5.131 |
| Gene length, protein length | 1056 bp, 352 aa |
| Immediate neighbours | ydcQ , ydcS |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04870
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: plasmid replication initiation factor family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P96635
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Catherine A Lee, Ana Babic, Alan D Grossman
Autonomous plasmid-like replication of a conjugative transposon.
Mol Microbiol: 2010, 75(2);268-79
[PubMed:19943900]
[WorldCat.org]
[DOI]
(I p)
Catherine A Lee, Alan D Grossman
Identification of the origin of transfer (oriT) and DNA relaxase required for conjugation of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
J Bacteriol: 2007, 189(20);7254-61
[PubMed:17693500]
[WorldCat.org]
[DOI]
(P p)
