AzoR2

• Description: similar to NAD(P)H dehydrogenase (quinone)
  
  

Gene name	azoR2
Synonyms	yvaB
Essential	no
Product	azoreductase
Function	resistance to 2-methylhydroquinone
MW, pI	23 kDa, 5.114
Gene length, protein length	633 bp, 211 aa
Immediate neighbours	yvaA, yvaC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33540

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: azoreductase type 1 family (according to Swiss-Prot)

• Paralogous protein(s): AzoR1

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3P0R (from B. anthracis, 43% identity, 61% similarity)

• UniProt: O32224

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: azoR2 PubMed

• Sigma factor: SigA PubMed, SigG PubMed

• Regulation:
  • induced by catechol and 2-methylhydroquinone (2-MHQ) (MhqR) PubMed
  • repressed by casamino acids PubMed

• Regulatory mechanism:
  • MhqR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: