GdpP

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  • Description: cyclic dinucleotide phosphodiesterase, involved in stress signaling and response

Gene name yybT
Synonyms
Essential no
Product cyclic dinucleotide phosphodiesterase
Function unknown
MW, pI 74 kDa, 4.865
Gene length, protein length 1977 bp, 659 aa
Immediate neighbours rplI, yybS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YybT context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

metabolism of signalling nucleotides

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cyclic dinucleotide phosphodiesterase, hydrolysis of di-cyclic AMP PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: ppGpp inhibits cyclic dinucleotide phosphodiesterase activity PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Feng Rao, Rui Yin See, Dongwei Zhang, Delon Chengxu Toh, Qiang Ji, Zhao-Xun Liang
YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity.
J Biol Chem: 2010, 285(1);473-82
[PubMed:19901023] [WorldCat.org] [DOI] (I p)