YrpC

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  • Description: glutamate racemase

Gene name yrpC
Synonyms
Essential no
Product glutamate racemase
Function peptidoglycan precursor biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 29 kDa, 6.74
Gene length, protein length 795 bp, 265 aa
Immediate neighbours yrpB, yrpD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YrpC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU26810

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamate = D-glutamate (according to Swiss-Prot)
  • Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2JFN (from Escherichia coli, 36% identity, 54% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation: expressed only in minimal medium, not in complex medium PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Keitarou Kimura, Lam-Son Phan Tran, Yoshifumi Itoh
Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 9);2911-2920
[PubMed:15347750] [WorldCat.org] [DOI] (P p)