RsbP

• Description: protein serine phosphatase, energy PP2C, dephosphorylates RsbV
  
  

Gene name	rsbP
Synonyms	yvfP
Essential	no
Product	protein serine phosphatase, energy PP2C
Function	control of SigB activity
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	45 kDa, 4.827
Gene length, protein length	1209 bp, 403 aa
Immediate neighbours	rsbQ, yvfO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU34110

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

protein modification, sigma factors and their control

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: dephosphorylation of RsbV in response to red light, this results in SigB activation PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RsbP-RsbV PubMed, RsbQ-RsbP

• Localization:

Database entries

• Structure:

• UniProt: O07014

• KEGG entry: [2]

• E.C. number: 3.1.3.3

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Chet Price, Davis, USA homepage

References

Reviews

Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979] [WorldCat.org] [DOI] (I p)