KtrC

• Description: low affinity potassium transporter KtrC-KtrD, peripheric membrane component
  
  

Gene name	ktrC
Synonyms	ylxV, yzaC, ykqB
Essential	no
Product	low affinity potassium transporter KtrC-KtrD, peripheric membrane component (proton symport)
Function	potassium uptake
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	24 kDa, 5.63
Gene length, protein length	663 bp, 221 aa
Immediate neighbours	ykqA, adeC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU14510

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: RCK N-terminal domain (according to Swiss-Prot)

• Paralogous protein(s): KtrA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: KtrC-KtrD PubMed

• Localization: cell membrane (according to Swiss-Prot), peripheral membrane protein PubMed

Database entries

• Structure:

• UniProt: P39760

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ktrC PubMed

• Sigma factor:

• Regulation: constitutively expressed PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

References

Gudrun Holtmann, Evert P Bakker, Nobuyuki Uozumi, Erhard Bremer
KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in adaptation to hypertonicity.
J Bacteriol: 2003, 185(4);1289-98
[PubMed:12562800] [WorldCat.org] [DOI] (P p)