DnaX

• Description: DNA polymerase III (gamma and tau subunits) part of the replisome
  
  

Gene name	dnaX
Synonyms	dnaH, dna-8132
Essential	yes PubMed
Product	DNA polymerase III (gamma and tau subunits)
Function	DNA replication
MW, pI	62 kDa, 5.488
Gene length, protein length	1689 bp, 563 aa
Immediate neighbours	scr, yaaK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU00190

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

DNA replication, essential genes

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: DnaX-DnaB PubMed, part of the replisome: PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed

• Localization: Nucleoid (Mid-cell) PubMed nucleoid region (mid-cell spot) PubMed

Database entries

• Structure:

• UniProt: P09122

• KEGG entry: [2]

• E.C. number: 2.7.7.7

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: