Dgk

• Description: deoxyguanosine kinase
  
  

Gene name	dgk
Synonyms	yaaG
Essential	no
Product	deoxyguanosine kinase
Function	purine salvage and interconversion
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation)
MW, pI	23 kDa, 5.783
Gene length, protein length	621 bp, 207 aa
Immediate neighbours	dck, yaaH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU00150

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P37530

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dgk-dck
• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

R B Andersen, J Neuhard
Deoxynucleoside kinases encoded by the yaaG and yaaF genes of Bacillus subtilis. Substrate specificity and kinetic analysis of deoxyguanosine kinase with UTP as the preferred phosphate donor.
J Biol Chem: 2001, 276(8);5518-24
[PubMed:11078735] [WorldCat.org] [DOI] (P p)