Adk

• Description: adenylate kinase
  
  

Gene name	adk
Synonyms
Essential	yes PubMed
Product	adenylate kinase
Function	ADP formation
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation)
MW, pI	23 kDa, 4.449
Gene length, protein length	651 bp, 217 aa
Immediate neighbours	secY, map
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU01370

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, essential genes

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + AMP = 2 ADP (according to Swiss-Prot)

• Protein family: adenylate kinase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1P3J

• UniProt: P16304

• KEGG entry: [2]

• E.C. number: 2.7.4.3 2.7.4.3]

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: