Sandbox

Mycoplasmas as minimal organisms

Sebastian R Schmidl, Katrin Gronau, Nico Pietack, Michael Hecker, Dörte Becher, Jörg Stülke
The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases.
Mol Cell Proteomics: 2010, 9(6);1228-42
[PubMed:20097688] [WorldCat.org] [DOI] (I p)

Sebastian Kühner, Vera van Noort, Matthew J Betts, Alejandra Leo-Macias, Claire Batisse, Michaela Rode, Takuji Yamada, Tobias Maier, Samuel Bader, Pedro Beltran-Alvarez, Daniel Castaño-Diez, Wei-Hua Chen, Damien Devos, Marc Güell, Tomas Norambuena, Ines Racke, Vladimir Rybin, Alexander Schmidt, Eva Yus, Ruedi Aebersold, Richard Herrmann, Bettina Böttcher, Achilleas S Frangakis, Robert B Russell, Luis Serrano, Peer Bork, Anne-Claude Gavin
Proteome organization in a genome-reduced bacterium.
Science: 2009, 326(5957);1235-40
[PubMed:19965468] [WorldCat.org] [DOI] (I p)

Sven Halbedel, Claudine Hames, Jörg Stülke
Regulation of carbon metabolism in the mollicutes and its relation to virulence.
J Mol Microbiol Biotechnol: 2007, 12(1-2);147-54
[PubMed:17183222] [WorldCat.org] [DOI] (P p)

Identification of a minimal gene set

Yusuke Azuma, Motonori Ota
An evaluation of minimal cellular functions to sustain a bacterial cell.
BMC Syst Biol: 2009, 3;111
[PubMed:19943949] [WorldCat.org] [DOI] (I e)

Steps on the way to an artificial organism

Daniel G Gibson, John I Glass, Carole Lartigue, Vladimir N Noskov, Ray-Yuan Chuang, Mikkel A Algire, Gwynedd A Benders, Michael G Montague, Li Ma, Monzia M Moodie, Chuck Merryman, Sanjay Vashee, Radha Krishnakumar, Nacyra Assad-Garcia, Cynthia Andrews-Pfannkoch, Evgeniya A Denisova, Lei Young, Zhi-Qing Qi, Thomas H Segall-Shapiro, Christopher H Calvey, Prashanth P Parmar, Clyde A Hutchison, Hamilton O Smith, J Craig Venter
Creation of a bacterial cell controlled by a chemically synthesized genome.
Science: 2010, 329(5987);52-6
[PubMed:20488990] [WorldCat.org] [DOI] (I p)

Carole Lartigue, Sanjay Vashee, Mikkel A Algire, Ray-Yuan Chuang, Gwynedd A Benders, Li Ma, Vladimir N Noskov, Evgeniya A Denisova, Daniel G Gibson, Nacyra Assad-Garcia, Nina Alperovich, David W Thomas, Chuck Merryman, Clyde A Hutchison, Hamilton O Smith, J Craig Venter, John I Glass
Creating bacterial strains from genomes that have been cloned and engineered in yeast.
Science: 2009, 325(5948);1693-6
[PubMed:19696314] [WorldCat.org] [DOI] (I p)

Daniel G Gibson, Gwynedd A Benders, Cynthia Andrews-Pfannkoch, Evgeniya A Denisova, Holly Baden-Tillson, Jayshree Zaveri, Timothy B Stockwell, Anushka Brownley, David W Thomas, Mikkel A Algire, Chuck Merryman, Lei Young, Vladimir N Noskov, John I Glass, J Craig Venter, Clyde A Hutchison, Hamilton O Smith
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.
Science: 2008, 319(5867);1215-20
[PubMed:18218864] [WorldCat.org] [DOI] (I p)

Carole Lartigue, John I Glass, Nina Alperovich, Rembert Pieper, Prashanth P Parmar, Clyde A Hutchison, Hamilton O Smith, J Craig Venter
Genome transplantation in bacteria: changing one species to another.
Science: 2007, 317(5838);632-8
[PubMed:17600181] [WorldCat.org] [DOI] (I p)

Metabolism

Frederik M Meyer, Jan Gerwig, Elke Hammer, Christina Herzberg, Fabian M Commichau, Uwe Völker, Jörg Stülke
Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon.
Metab Eng: 2011, 13(1);18-27
[PubMed:20933603] [WorldCat.org] [DOI] (I p)

Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley M Deacon, John Wooley, Scott A Lesley, Ian A Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik
Three-dimensional structural view of the central metabolic network of Thermotoga maritima.
Science: 2009, 325(5947);1544-9
[PubMed:19762644] [WorldCat.org] [DOI] (I p)

Bryson D Bennett, Elizabeth H Kimball, Melissa Gao, Robin Osterhout, Stephen J Van Dien, Joshua D Rabinowitz
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.
Nat Chem Biol: 2009, 5(8);593-9
[PubMed:19561621] [WorldCat.org] [DOI] (I p)

Wataru Iwasaki, Toshihisa Takagi
Rapid pathway evolution facilitated by horizontal gene transfers across prokaryotic lineages.
PLoS Genet: 2009, 5(3);e1000402
[PubMed:19266023] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632] [WorldCat.org] [DOI] (I p)

Armen Y Mulkidjanian, Eugene V Koonin, Kira S Makarova, Sergey L Mekhedov, Alexander Sorokin, Yuri I Wolf, Alexis Dufresne, Frédéric Partensky, Henry Burd, Denis Kaznadzey, Robert Haselkorn, Michael Y Galperin
The cyanobacterial genome core and the origin of photosynthesis.
Proc Natl Acad Sci U S A: 2006, 103(35);13126-31
[PubMed:16924101] [WorldCat.org] [DOI] (P p)

M Ribbe, D Gadkari, O Meyer
N2 fixation by Streptomyces thermoautotrophicus involves a molybdenum-dinitrogenase and a manganese-superoxide oxidoreductase that couple N2 reduction to the oxidation of superoxide produced from O2 by a molybdenum-CO dehydrogenase.
J Biol Chem: 1997, 272(42);26627-33
[PubMed:9334244] [WorldCat.org] [DOI] (P p)

Marcus Richter

Yunrong Chai, Thomas Norman, Roberto Kolter, Richard Losick
An epigenetic switch governing daughter cell separation in Bacillus subtilis.
Genes Dev: 2010, 24(8);754-65
[PubMed:20351052] [WorldCat.org] [DOI] (I p)

Daniel Lopez, Hera Vlamakis, Roberto Kolter
Generation of multiple cell types in Bacillus subtilis.
FEMS Microbiol Rev: 2009, 33(1);152-63
[PubMed:19054118] [WorldCat.org] [DOI] (P p)

Dominik Tödter

Franck Pandiani, Julien Brillard, Isabelle Bornard, Caroline Michaud, Stéphanie Chamot, Christophe Nguyen-the, Véronique Broussolle
Differential involvement of the five RNA helicases in adaptation of Bacillus cereus ATCC 14579 to low growth temperatures.
Appl Environ Microbiol: 2010, 76(19);6692-7
[PubMed:20709848] [WorldCat.org] [DOI] (I p)

Martin Lehnik-Habrink, Henrike Pförtner, Leonie Rempeters, Nico Pietack, Christina Herzberg, Jörg Stülke
The RNA degradosome in Bacillus subtilis: identification of CshA as the major RNA helicase in the multiprotein complex.
Mol Microbiol: 2010, 77(4);958-71
[PubMed:20572937] [WorldCat.org] [DOI] (I p)

Sanda Rocak, Patrick Linder
DEAD-box proteins: the driving forces behind RNA metabolism.
Nat Rev Mol Cell Biol: 2004, 5(3);232-41
[PubMed:14991003] [WorldCat.org] [DOI] (P p)