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Mycoplasmas as minimal organisms


Identification of a minimal gene set


Steps on the way to an artificial organism

Daniel G Gibson, John I Glass, Carole Lartigue, Vladimir N Noskov, Ray-Yuan Chuang, Mikkel A Algire, Gwynedd A Benders, Michael G Montague, Li Ma, Monzia M Moodie, Chuck Merryman, Sanjay Vashee, Radha Krishnakumar, Nacyra Assad-Garcia, Cynthia Andrews-Pfannkoch, Evgeniya A Denisova, Lei Young, Zhi-Qing Qi, Thomas H Segall-Shapiro, Christopher H Calvey, Prashanth P Parmar, Clyde A Hutchison, Hamilton O Smith, J Craig Venter
Creation of a bacterial cell controlled by a chemically synthesized genome.
Science: 2010, 329(5987);52-6
[PubMed:20488990] [WorldCat.org] [DOI] (I p)

Carole Lartigue, Sanjay Vashee, Mikkel A Algire, Ray-Yuan Chuang, Gwynedd A Benders, Li Ma, Vladimir N Noskov, Evgeniya A Denisova, Daniel G Gibson, Nacyra Assad-Garcia, Nina Alperovich, David W Thomas, Chuck Merryman, Clyde A Hutchison, Hamilton O Smith, J Craig Venter, John I Glass
Creating bacterial strains from genomes that have been cloned and engineered in yeast.
Science: 2009, 325(5948);1693-6
[PubMed:19696314] [WorldCat.org] [DOI] (I p)

Daniel G Gibson, Gwynedd A Benders, Cynthia Andrews-Pfannkoch, Evgeniya A Denisova, Holly Baden-Tillson, Jayshree Zaveri, Timothy B Stockwell, Anushka Brownley, David W Thomas, Mikkel A Algire, Chuck Merryman, Lei Young, Vladimir N Noskov, John I Glass, J Craig Venter, Clyde A Hutchison, Hamilton O Smith
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.
Science: 2008, 319(5867);1215-20
[PubMed:18218864] [WorldCat.org] [DOI] (I p)

Carole Lartigue, John I Glass, Nina Alperovich, Rembert Pieper, Prashanth P Parmar, Clyde A Hutchison, Hamilton O Smith, J Craig Venter
Genome transplantation in bacteria: changing one species to another.
Science: 2007, 317(5838);632-8
[PubMed:17600181] [WorldCat.org] [DOI] (I p)


Metabolism


Systematics