YlaC

• Description: RNA polymerase ECF-type sigma factor YlaC
  
  

Gene name	ylaC
Synonyms
Essential	no
Product	RNA polymerase ECF-type sigma factor YlaC
Function	transcription
MW, pI	20 kDa, 9.282
Gene length, protein length	519 bp, 173 aa
Immediate neighbours	ylaB, ylaD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU14730

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ECF subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: YlaD acts as anti-sigma PubMed

• Interactions: YlaC-YlaD PubMed, YlaC-RpoB-RpoC

• Localization:

Database entries

• Structure:

• UniProt: O07627

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ylaA-ylaB-ylaC-ylaD PubMed
  • ylaC-ylaD PubMed

• Sigma factor:
  • ylaA: YlaC PubMed
  • ylaC: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383] [WorldCat.org] [DOI] (P p)

Han-Bong Ryu, Inji Shin, Hyung-Soon Yim, Sa-Ouk Kang
YlaC is an extracytoplasmic function (ECF) sigma factor contributing to hydrogen peroxide resistance in Bacillus subtilis.
J Microbiol: 2006, 44(2);206-16
[PubMed:16728958] [WorldCat.org] (P p)

Takashi Matsumoto, Kaoru Nakanishi, Kei Asai, Yoshito Sadaie
Transcriptional analysis of the ylaABCD operon of Bacillus subtilis encoding a sigma factor of extracytoplasmic function family.
Genes Genet Syst: 2005, 80(6);385-93
[PubMed:16501307] [WorldCat.org] [DOI] (P p)