PucH

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  • Description: allantoinase

Gene name pucH
Synonyms yunH
Essential no
Product allantoinase
Function purine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Nucleotides (regulation)
MW, pI 48 kDa, 5.062
Gene length, protein length 1338 bp, 446 aa
Immediate neighbours yunG, pucR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucH context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU32410

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-allantoin + H2O = allantoate (according to Swiss-Prot)
  • Protein family: Allantoinase subfamily (according to Swiss-Prot)
  • Paralogous protein(s): PyrC

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 3HM7 (from Bacillus halodurans, 44% identity, 65% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References