Tlp

• Description: thioredoxin-like protein
  
  

Gene name	tlp
Synonyms
Essential	no
Product	thioredoxin-like protein
Function	unknown
MW, pI	9 kDa, 4.439
Gene length, protein length	249 bp, 83 aa
Immediate neighbours	nucA, yneP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU18030

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: tlp family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: spore core (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q45060

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sspN-tlp PubMed

• Sigma factor: SigF PubMed, SigG PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

A Cabrera-Hernandez, J L Sanchez-Salas, M Paidhungat, P Setlow
Regulation of four genes encoding small, acid-soluble spore proteins in Bacillus subtilis.
Gene: 1999, 232(1);1-10
[PubMed:10333516] [WorldCat.org] [DOI] (P p)