ResE

• Description: two-component sensor kinase, regulation of aerobic and anaerobic respiration
  
  

Gene name	resE
Synonyms	ypxE
Essential	no
Product	two-component sensor kinase
Function	regulation of aerobic and anaerobic respiration
MW, pI	66 kDa, 5.344
Gene length, protein length	1767 bp, 589 aa
Immediate neighbours	sigX, resD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU23110

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P35164

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: resA-resB-resC-resD-resE

• Sigma factor: SigA

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed
  • repressed when phosphate is available (PhoP) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed
  • PhoP: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: