AhrC

• Description: AhrC represses the synthesis of biosynthetic enzymes and activates the arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF
  
  

Gene name	ahrC
Synonyms	argR
Essential	no
Product	transcriptional regulator
Function	transcriptional regulator of arginine metabolism expression
MW, pI	16,7 kDa, 5.52
Gene length, protein length	447 bp, 149 amino acids
Immediate neighbours	yqxC, recN
Gene sequence (+200bp)	Protein sequence
Genetic context File:GenE context.gif

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcriptional regulator of arginine metabolism expression

• Protein family: argR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: Cytoplasm

Database entries

• Structure: NCBI

• Swiss prot entry: [3]

• KEGG entry: [4]

Expression and regulation

• Operon: ahrC-recN

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

References

1. Van Hoy BE et al. (1990) Characterization of the spoIVB and recN loci of Bacillus subtilis J Bacteriol. 172: 1306-1311. PubMed
2. Heidrich et al. (2006) The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism. Mol. Microbiol. 62: 520-536. PubMed
3. Heidrich et al. (2007) In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA. Nucl. Acids Res. 35: 4331-4346. PubMed