Rtp

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  • Description: replication terminator protein

Gene name rtp
Synonyms
Essential no
Product replication terminator protein
Function replication termination
MW, pI 14 kDa, 9.778
Gene length, protein length 366 bp, 122 aa
Immediate neighbours ycbJ, ycbK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Rtp context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 1F4K (complex with DNA), 1BM9
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Autret, A Levine, F Vannier, Y Fujita, S J Séror
The replication checkpoint control in Bacillus subtilis: identification of a novel RTP-binding sequence essential for the replication fork arrest after induction of the stringent response.
Mol Microbiol: 1999, 31(6);1665-79
[PubMed:10209741] [WorldCat.org] [DOI] (P p)

A Levine, S Autret, S J Séror
A checkpoint involving RTP, the replication terminator protein, arrests replication downstream of the origin during the Stringent Response in Bacillus subtilis.
Mol Microbiol: 1995, 15(2);287-95
[PubMed:7746150] [WorldCat.org] [DOI] (P p)

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed