TreP

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  • Description: trehalose-specific phosphotransferase system, EIIBC component

Gene name treP
Synonyms treB
Essential no
Product trehalose-specific phosphotransferase system, EIIBC component
Function trehalose uptake and phosphorylation
MW, pI 49 kDa, 8.555
Gene length, protein length 1410 bp, 470 aa
Immediate neighbours yfkQ, treA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TreP context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU07800

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
  • Protein family: PTS permease, sucrose permease (Scr) family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Reizer et al. (1999) Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis. Microbiology 145: 3419-3429 PubMed
  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed