TrpS
- Description: tryptophany-tRNA synthetase
Gene name | trpS |
Synonyms | |
Essential | yes PubMed |
Product | tryptophany-tRNA synthetase |
Function | translation |
MW, pI | 37 kDa, 6.542 |
Gene length, protein length | 990 bp, 330 aa |
Immediate neighbours | yjbA, oppA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp) (according to Swiss-Prot)
- Protein family: class-I aminoacyl-tRNA synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1BM2 (complex with tryptophan, Geobacillus stearothermophilus), 1MAW (complex with ATP, Geobacillus stearothermophilus)
- Swiss prot entry: P21656
- KEGG entry: BSU11420
- E.C. number: 6.1.1.2
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed