SdhB

• Description: succinate dehydrogenase
  
  

Gene name	sdhB
Synonyms
Essential	no
Product	succinate dehydrogenase (iron-sulfur protein)
Function	TCA cycle
MW, pI	28 kDa, 7.989
Gene length, protein length	759 bp, 253 aa
Immediate neighbours	sdhA, ysmA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Succinate + acceptor = fumarate + reduced acceptor (according to Swiss-Prot)

• Protein family: succinate dehydrogenase/fumarate reductase iron-sulfur protein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: SdhA-SdhB-SdhC

• Localization: attached to the membrane PubMed

Database entries

• Structure: 1NEK (E. coli)

• Swiss prot entry: P08066

• KEGG entry: BSU28430

• E.C. number:EC 1.3.99.1

Expression and regulation

• Operon: sdhC-sdhA-sdhB PubMed

• Sigma factor: SigA PubMed

• Regulation: constitutive

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed