SwrAA/1

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  • Description: control of motility, enhances sigD transcription

Gene name swrAA
Synonyms yvzD
Essential no
Product swarming motility protein
Function essential for �swarming differentiation� on solid surfaces
MW, pI 13 kDa, 8.4
Gene length, protein length 336 bp, 112 aa
Immediate neighbours minJ, ctpB
Gene sequence (+200bp) Protein sequence
Genetic context
YvzD context.gif
This image was kindly provided by SubtiList
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm.

The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.

The protein

Basic information/ Evolution

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  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
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  • Modification:
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  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

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Additional information

Expression and regulation

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  • Regulation:
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Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Cecilia Osera, Giuseppe Amati, Cinzia Calvio, Alessandro Galizzi
SwrAA activates poly-gamma-glutamate synthesis in addition to swarming in Bacillus subtilis.
Microbiology (Reading): 2009, 155(Pt 7);2282-2287
[PubMed:19389763] [WorldCat.org] [DOI] (P p)