PatB

• Description: cystathione-�-lyase
  
  

Gene name	patB
Synonyms
Essential	no
Product	cystathione-�-lyase
Function	biosynthesis of methionine
MW, pI	42 kDa, 5.439
Gene length, protein length	1161 bp, 387 aa
Immediate neighbours	yugE, kinB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-cystathionine + H₂O = L-homocysteine + NH₃ + pyruvate (according to Swiss-Prot)

• Protein family: MalY/patB cystathionine beta-lyase subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: Q08432

• KEGG entry: BSU31440

• E.C. number: 4.4.1.8

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Auger S, Gomez MP, Danchin A, Martin-Verstraete I. (2005) The PatB protein of Bacillus subtilis is a C-S-lyase. Biochimie Feb;87(2): 231-8. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed