Sandbox

• Description: replicative DNA helicase
  
  

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Gene name

dnaC

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Synonyms

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Essential

yes PubMed

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Product

replicative DNA helicase

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Function

DNA replication

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MW, pI

50 kDa, 4.548

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Gene length, protein length

1362 bp, 454 aa

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Immediate neighbours

yycE, yycD

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Hier soll was neues rein

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Genetic context This image was kindly provided by SubtiList

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The gene

Basic information

• Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: DnaI|-DnaC PubMed

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two|-hybrid system:

• Antibody:

References

1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135|-2146. PubMed
2. Imai et al. (2000) Subcellular localization of Dna|-initiation proteins of Bacillus subtilis: evidence that chromosome replication begins at either edge of the nucleoids. Mol. Microbiol. 36: 1037|-1048. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page|-page. PubMed