Stusti 2018

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

• Riboswitches

• Riboregulation and virulence, targeting by antibiotics

• RNA-based second messengers

Jan Gundlach, Christina Herzberg, Volkhard Kaever, Katrin Gunka, Tamara Hoffmann, Martin Weiß, Johannes Gibhardt, Andrea Thürmer, Dietrich Hertel, Rolf Daniel, Erhard Bremer, Fabian M Commichau, Jörg Stülke
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Sci Signal: 2017, 10(475);
[PubMed:28420751] [WorldCat.org] [DOI] (I e)

Christopher P Jones, Adrian R Ferré-D'Amaré
Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains.
Nat Struct Mol Biol: 2015, 22(9);679-85
[PubMed:26280533] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Achim Dickmanns, Jan Gundlach, Ralf Ficner, Jörg Stülke
A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.
Mol Microbiol: 2015, 97(2);189-204
[PubMed:25869574] [WorldCat.org] [DOI] (I p)

Renée J St-Onge, Henry J Haiser, Mary R Yousef, Emma Sherwood, Natalia Tschowri, Mahmoud Al-Bassam, Marie A Elliot
Nucleotide second messenger-mediated regulation of a muralytic enzyme in Streptomyces.
Mol Microbiol: 2015, 96(4);779-95
[PubMed:25682701] [WorldCat.org] [DOI] (I p)

Gregory S Ducker, Joshua D Rabinowitz
ZMP: a master regulator of one-carbon metabolism.
Mol Cell: 2015, 57(2);203-4
[PubMed:25616065] [WorldCat.org] [DOI] (I p)

• Ribozymes

• Protein- or tRNA-controlled RNA switches

• RNA thermometers

• The RNA world and evolution

• RNA modification

• RNA degradation/ processing

John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538] [WorldCat.org] [DOI] (I p)

• CRISPR/Cas: Science

• CRISPR/Cas: Application