FlgB

• Description: flagellar basal-body rod protein
  
  

Gene name	flgB
Synonyms
Essential	no
Product	flagellar basal-body rod protein
Function	movement and chemotaxis
Gene expression levels in SubtiExpress: flgB
MW, pI	14 kDa, 5.165
Gene length, protein length	387 bp, 129 aa
Immediate neighbours	codY, flgC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

• Locus tag: BSU16180

Database entries

• BsubCyc: BSU16180

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flagella basal body rod proteins family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: bacterial flagellum basal body (according to Swiss-Prot), extracellular (no signal peptide) PubMed

Database entries

• BsubCyc: BSU16180

• Structure:

• UniProt: P24500

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed

• Expression browser: flgB PubMed

• Sigma factor: SigA PubMed, SigD PubMed

• Regulation:
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed
  • CodY: transcription repression PubMed
  • DegU (non-phosphorylated): transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • a flgB::erm mutant is available in Linc Sonenshein's lab
  • 1A922 ( flgB::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: