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Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!

Contact: General Microbiology, University of Göttingen, send mail

Upcoming events:

The BACELL meeting 2015, organized by Leendert Hamoen will take place from April 14 to 15 in Amsterdam, The Netherlands. Contact
The International Conference on Metabolic Engineering, organized by Ivan Mijakovic and Leendert Hamoen will take place from April 16 to 17 in Amsterdam, The Netherlands. Contact
The 8th International Conference on Gram-positive Microorganisms (18th International Conference on Bacilli) in Montecatini Terme, organized by Marta Perego, Jim Hoch, and Hendrik Szurmant will take place from June 21 to 25. Conference website
Past conferences

New: Subtiwiki is now on Facebook - please give it a +1!

Now online: A new description of SubtiWiki and its acompanying modules in the 2014 Database issue of Nucleic Acids Research

Paper of the month: November 2014

Integration of prophages into coding sequences of the host genome results in loss of function of the interrupted gene. In B. subtilis 168, the SP-beta prophage is inserted into a uncharacterized spore polysaccharide synthesis gene, spsM. In vegetative cells, the lytic cycle is induced in response to DNA damage. In the process, the SP-beta prophage is excised from the genome to form phage particles. Now, Abe et al. demonstrate that the excision of the SP-beta prophage also occurs systematically during sporulation to reconstitute a functional spsM gene from the incomplete yodU and ypqP pseudogenes. Because phage excision is limited to the mother cell genome, and does not occur in the forespore genome, the SP-beta prophage is an integral part of the spore genome. Thus, after germination, the SP-beta prophage is propagated vertically to the progeny. The authors suggest their results indicate that the two pathways of SP-beta prophage excision support both the phage life cycle and normal sporulation of the host cells.
Relevant SubtiWiki pages: SP-beta prophage, sporulation, yodU, ypqP, SprA, SprB

New procedure for account creation:

Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!

News in SubtiWiki:

August 2014: The first mobile application for SubtiWiki is now available for users of Android phones: Go for SubtiWiki in Google Play! IPhone users, please be patient! You will be served next! Click here to install!
April 2013: SubtiWiki uses a new, faster Mediawiki platform! The times for page access are significantly reduced. Enjoy!
March 2013: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
October 2012: the essential genes have been categorized
September 2012: 300 mutant strains available at the BGSC were added to the corresponding gene pages
August 2012: SubtiExpress, the new compagnon of SubtiWiki devoted to gene expression is online! Try it out!
April 2012: Links for expression data under 104 different conditions (based on Nicolas et al., 2012) have been added to the expression section of the individual gene pages
April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways

Publications describing SubtiWiki and SubtiPathways:

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