SpsJ

• Description: dTDP -glucose-4,6-dehydratase, spore coat polysaccharide synthesis
  
  

Gene name	spsJ
Synonyms	ipa-72d
Essential	no
Product	dTDP -glucose-4,6-dehydratase
Function	rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsJ
MW, pI	35 kDa, 6.286
Gene length, protein length	945 bp, 315 aa
Immediate neighbours	spsK, spsI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU37830

Database entries

• BsubCyc: BSU37830

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • dTDP-glucose --> dTDP-4-dehydro-6-deoxyglucose PubMed

• Protein family: sugar epimerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU37830

• Structure:

• UniProt: P39630

• KEGG entry: [3]

• E.C. number: 4.2.1.46

Expression and regulation

• Operon: spsA-spsB-spsC-spsD-spsF-spsG-spsI-spsJ-spsK-spsL PubMed

• Expression browser: spsJ PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: