Tdh

• Description: L-threonine dehydrogenase
  
  

Gene name	tdh
Synonyms
Essential	no
Product	L-threonine dehydrogenase
Function	threonine utilization
Gene expression levels in SubtiExpress: tdh
Metabolic function and regulation of this protein in SubtiPathways: tdh
MW, pI	36 kDa, 6.061
Gene length, protein length	1041 bp, 347 aa
Immediate neighbours	spoVS, kbl
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of amino acids

The gene

Basic information

• Locus tag: BSU16990

Database entries

• BsubCyc: BSU16990

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-threonine + NAD⁺ = L-2-amino-3-oxobutanoate + NADH (according to Swiss-Prot)

• Protein family: zinc-containing alcohol dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU16990

• Structure: 2DQ4 (from Thermus thermophilus, 47% identity, 63% similarity)

• UniProt: O31776

• KEGG entry: [2]

• E.C. number: 1.1.1.103

Expression and regulation

• Operon:

• Expression browser: tdh PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: