YetL

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  • Description: transcriptional repressor of yetM and yetL, induction in response to flavonoids

Gene name yetL
Synonyms
Essential no
Product transcription repressor (MarR family)
Function regulation of yetM expression
Gene expression levels in SubtiExpress: yetL
MW, pI 19 kDa, 7.518
Gene length, protein length 501 bp, 167 aa
Immediate neighbours yetK, yetM
Sequences Protein DNA DNA_with_flanks
Genetic context
YetL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YetL expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

The YetL regulon:

The gene

Basic information

  • Locus tag: BSU07220

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: inducers: flavonoids of kaempferol, apigenin, and luteolin PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kazutake Hirooka, Yusuke Danjo, Yuki Hanano, Satoshi Kunikane, Hiroshi Matsuoka, Shigeo Tojo, Yasutaro Fujita
Regulation of the Bacillus subtilis divergent yetL and yetM genes by a transcriptional repressor, YetL, in response to flavonoids.
J Bacteriol: 2009, 191(11);3685-97
[PubMed:19329649] [WorldCat.org] [DOI] (I p)