YxkO

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  • Description: ADP/ATP-dependent NAD(P)H-hydrate dehydratase, general stress protein, survival of ethanol stress

Gene name yxkO
Synonyms
Essential no
Product ADP/ATP-dependent NAD(P)H-hydrate dehydratase
Function survival of ethanol stress
Gene expression levels in SubtiExpress: yxkO
MW, pI 29 kDa, 5.488
Gene length, protein length 828 bp, 276 aa
Immediate neighbours yxlA, cydD
Sequences Protein DNA DNA_with_flanks
Genetic context
YxkO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YxkO expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU38720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Igor A Shumilin, Marcin Cymborowski, Olga Chertihin, Kula N Jha, John C Herr, Scott A Lesley, Andrzej Joachimiak, Wladek Minor
Identification of unknown protein function using metabolite cocktail screening.
Structure: 2012, 20(10);1715-25
[PubMed:22940582] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

R-g Zhang, J Grembecka, E Vinokour, F Collart, I Dementieva, W Minor, A Joachimiak
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase.
J Struct Biol: 2002, 139(3);161-70
[PubMed:12457846] [WorldCat.org] [DOI] (P p)

Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760] [WorldCat.org] [DOI] (P p)