DapF

• Description: diaminopimelate epimerase
  
  

Gene name	dapF
Synonyms	yutL
Essential	yes PubMed
Product	diaminopimelate epimerase
Function	biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: dapF
Metabolic function and regulation of this protein in SubtiPathways: dapF
MW, pI	30 kDa, 4.506
Gene length, protein length	852 bp, 284 aa
Immediate neighbours	sufA, yutK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes

The gene

Basic information

• Locus tag: BSU32170

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: LL-diaminopimelate --> meso-diaminopimelate

• Protein family: diaminopimelate epimerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2OTN (from Bacillus anthracis str. ames, 62% identity, 75% similarity)

• UniProt: O32114

• KEGG entry: [2]

• E.C. number: 5.1.1.7

Expression and regulation

• Operon:

• Expression browser: dapF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: