NagR

• Description: transcriptional regulator (GntR family)
  
  

Gene name	nagR
Synonyms	yvoA
Essential	no
Product	transcriptional regulator (GntR family)
Function	probably regulator of the putative nagA-nagB-yvoA operon
Gene expression levels in SubtiExpress: nagR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism, Murein recycling
MW, pI	27 kDa, 6.768
Gene length, protein length	729 bp, 243 aa
Immediate neighbours	nagB, yvnB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

NagR regulon

The NagR regulon:

• nagA-nagB-nagR, nagP

The gene

Basic information

• Locus tag: BSU35030

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription repression of nagP and of the putative nagA-nagB-nagR operon in the absence of N-acetylglycosamine PubMed, weak repression of yflG PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information: K(D) for N-acetylglucosamine-6-phosphate: 1 mM PubMed

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:
  • N-acetylglucosamine-6-phosphate acts as the molecular inducer PubMed
  • glucosamine-6-phosphate acts as the molecular inducerPubMed

• Interactions:

• Localization:

Database entries

• Structure: 2WVO PubMed

• UniProt: O34817

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: nagA-nagB-nagR PubMed

• Expression browser: nagR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced in the presence of N-acetylglucosamine (NagR) PubMed

• Regulatory mechanism:
  • NagR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: