OxdD

• Description: oxalate decarboxylase, inner spore coat protein
  
  

Gene name	oxdD
Synonyms	yoaN
Essential	no
Product	oxalate decarboxylase
Function	protection of the spore
Gene expression levels in SubtiExpress: oxdD
MW, pI	43 kDa, 5.359
Gene length, protein length	1176 bp, 392 aa
Immediate neighbours	yozS, yoaO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

SigK regulon, GerE regulon

The gene

Basic information

• Locus tag: BSU18670

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Oxalate = formate + CO₂ (according to Swiss-Prot)

• Protein family: UPF0361 family (according to Swiss-Prot)

• Paralogous protein(s): OxdC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat, localization depends on SafA PubMed

Database entries

• Structure:

• UniProt: O34767

• KEGG entry: [3]

• E.C. number: 4.1.1.2

Expression and regulation

• Operon: oxdD PubMed

• Expression browser: oxdD PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

• Regulatory mechanism:
  • GerE: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Miia R Mäkelä, Kristiina Hildén, Taina K Lundell
Oxalate decarboxylase: biotechnological update and prevalence of the enzyme in filamentous fungi.
Appl Microbiol Biotechnol: 2010, 87(3);801-14
[PubMed:20464388] [WorldCat.org] [DOI] (I p)