FtsX

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Gene name ftsX
Synonyms
Essential no
Product ABC transporter (membrane protein)
Function control of cell wall synthesis
Gene expression levels in SubtiExpress: ftsX
Interactions involving this protein in SubtInteract: FtsX
MW, pI 32 kDa, 10.016
Gene length, protein length 888 bp, 296 aa
Immediate neighbours ctpB, ftsE
Sequences Protein DNA DNA_with_flanks
Genetic context
FtsX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FtsX expression.png















Categories containing this gene/protein

ABC transporters, cell wall synthesis, phosphorelay, membrane proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU35250

Phenotypes of a mutant

  • a ftsX mutation is synthetically lethal with a lytE mutation (due to a lack of autolysin activity) PubMed
  • shorter, fatter cells PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • necessary for the autolysin activity of CwlO PubMed
  • Protein family: FtsX subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References