YhcR

• Description: extracellular non-specific endonuclease, Rnase
  
  

Gene name	yhcR
Synonyms
Essential	no
Product	extracellular non-specific endonuclease, Rnase
Function	utilization of nucleic acids
Gene expression levels in SubtiExpress: yhcR
Interactions involving this protein in SubtInteract: YhcR
MW, pI	132 kDa, 4.693
Gene length, protein length	3651 bp, 1217 aa
Immediate neighbours	yhcQ, yhcS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, Rnases

The gene

Basic information

• Locus tag: BSU09190

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YfkN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YhcS-YhcR PubMed (anchoring to the cell wall)

• Localization: extracellular (signal peptide) PubMed, attached to the cell wall PubMed

Database entries

• Structure:

• UniProt: P54602

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhcR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage

References

Additional referencecs: PubMed

Hamidreza Fasehee, Helga Westers, Albert Bolhuis, Haike Antelmann, Michael Hecker, Wim J Quax, Agha F Mirlohi, Jan Maareten van Dijl, Gholamreza Ahmadian
Functional analysis of the sortase YhcS in Bacillus subtilis.
Proteomics: 2011, 11(19);3905-13
[PubMed:21800427] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Irina A Oussenko, Roberto Sanchez, David H Bechhofer
Bacillus subtilis YhcR, a high-molecular-weight, nonspecific endonuclease with a unique domain structure.
J Bacteriol: 2004, 186(16);5376-83
[PubMed:15292138] [WorldCat.org] [DOI] (P p)