LigD

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  • Description: confers dry-heat resistance to dormant spores PubMed, similar to ATP-dependent DNA ligase

Gene name ykoU
Synonyms
Essential no
Product unknown
Function confers dry-heat resistance to dormant spores
Gene expression levels in SubtiExpress: ykoU
MW, pI 70 kDa, 6.646
Gene length, protein length 1833 bp, 611 aa
Immediate neighbours ykoT, ykoV
Sequences Protein DNA DNA_with_flanks
Genetic context
YkoU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkoU expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigG regulon, SpoVT regulon


The gene

Basic information

  • Locus tag: BSU13400

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: C-terminal DNA ligase catalytic domain linked to an N-terminal polymerase domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Miguel de Vega
The minimal Bacillus subtilis nonhomologous end joining repair machinery.
PLoS One: 2013, 8(5);e64232
[PubMed:23691176] [WorldCat.org] [DOI] (I e)

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)