AadK

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  • Description: aminoglycoside 6-adenylyltransferase

Gene name aadK
Synonyms
Essential no
Product aminoglycoside 6-adenylyltransferase
Function resistance to streptomycin
Gene expression levels in SubtiExpress: aadK
MW, pI 33 kDa, 4.755
Gene length, protein length 852 bp, 284 aa
Immediate neighbours yrdA, yrpB
Sequences Protein DNA DNA_with_flanks
Genetic context
AadK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AadK expression.png
























Categories containing this gene/protein

resistance against toxins/ antibiotics

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU26790

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

N Noguchi, M Sasatsu, M Kono
Genetic mapping in Bacillus subtilis 168 of the aadK gene which encodes aminoglycoside 6-adenylyltransferase.
FEMS Microbiol Lett: 1993, 114(1);47-52
[PubMed:8293959] [WorldCat.org] [DOI] (P p)

K Ohmiya, T Tanaka, N Noguchi, K O'Hara, M Kono
Nucleotide sequence of the chromosomal gene coding for the aminoglycoside 6-adenylyltransferase from Bacillus subtilis Marburg 168.
Gene: 1989, 78(2);377-8
[PubMed:2550327] [WorldCat.org] [DOI] (P p)