EbrA

• Description: multidrug efflux transporter
  
  

Gene name	ebrA
Synonyms
Essential	no
Product	multidrug efflux transporter
Function	multidrug resistance
Gene expression levels in SubtiExpress: ebrA
Interactions involving this protein in SubtInteract: EbrA
MW, pI	11 kDa, 9.373
Gene length, protein length	315 bp, 105 aa
Immediate neighbours	ebrB, ymaG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU17300

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): EbrB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: EbrA-EbrB PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O31792

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ebrA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)