YlaC

• Description: RNA polymerase sigma factor YlaC
  
  

Gene name	ylaC
Synonyms
Essential	no
Product	RNA polymerase sigma factor YlaC
Function	transcription
Gene expression levels in SubtiExpress: ylaC
Interactions involving this protein in SubtInteract: YlaC
MW, pI	20 kDa, 9.282
Gene length, protein length	519 bp, 173 aa
Immediate neighbours	ylaB, ylaD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription, sigma factors and their control

This gene is a member of the following regulons

Spx regulon, YlaC regulon

The gene

Basic information

• Locus tag: BSU14730

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ECF subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: YlaD acts as anti-sigma PubMed

• Interactions:
  • YlaC-YlaD PubMed, YlaC-RpoB-RpoC

• Localization:

Database entries

• Structure:

• UniProt: O07627

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ylaA-ylaB-ylaC-ylaD PubMed
  • ylaC-ylaD PubMed

• Expression browser: ylaC PubMed

• Sigma factor:
  • ylaA: YlaC PubMed
  • ylaC: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A908 ( ylaC::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383] [WorldCat.org] [DOI] (P p)

Han-Bong Ryu, Inji Shin, Hyung-Soon Yim, Sa-Ouk Kang
YlaC is an extracytoplasmic function (ECF) sigma factor contributing to hydrogen peroxide resistance in Bacillus subtilis.
J Microbiol: 2006, 44(2);206-16
[PubMed:16728958] [WorldCat.org] (P p)

Takashi Matsumoto, Kaoru Nakanishi, Kei Asai, Yoshito Sadaie
Transcriptional analysis of the ylaABCD operon of Bacillus subtilis encoding a sigma factor of extracytoplasmic function family.
Genes Genet Syst: 2005, 80(6);385-93
[PubMed:16501307] [WorldCat.org] [DOI] (P p)