TreR

• Description: transcription repressor of the treP-treA-treR operon, (GntR family)
  
  

Gene name	treR
Synonyms	yfxA
Essential	no
Product	transcription repressor, (GntR family)
Function	regulation of trehalose utilization
Gene expression levels in SubtiExpress: treR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	27 kDa, 6.82
Gene length, protein length	714 bp, 238 aa
Immediate neighbours	treA, hypO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, TreR regulon

The TreR regulon

• treP-treA-treR

The gene

Basic information

• Locus tag: BSU07820

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2OGG (effector binding domain) PubMed

• UniProt: P39796

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: treP-treA-treR PubMed

• Expression browser: treR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by trehalose (TreR) PubMed
  • repressed by glucose (CcpA) PubMed
  • expressed under conditions of phosphate limitation (PhoP) PubMed

• Regulatory mechanism:
  • TreR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • PhoP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed