YflG

• Description: methionine aminopeptidase
  
  

Gene name	yflG
Synonyms
Essential	no
Product	methionine aminopeptidase
Function	removal of N-terminal methionine from nascent proteins
Gene expression levels in SubtiExpress: yflG
MW, pI	27 kDa, 5.578
Gene length, protein length	747 bp, 249 aa
Immediate neighbours	yflH, nagP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, protein modification

The gene

Basic information

• Locus tag: BSU07690

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)

• Protein family: peptidase M24A family (according to Swiss-Prot)

• Paralogous protein(s): Map

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34484

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yflG-yflH PubMed

• Expression browser: yflG PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • NagR: transcription repression (weak and not certain) PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin
The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.
BMC Microbiol: 2005, 5;57
[PubMed:16207374] [WorldCat.org] [DOI] (I e)