DsdA

• Description: D-serine deaminase
  
  

Gene name	dsdA
Synonyms	yqjR
Essential	no
Product	D-serine deaminase
Function	unknown
Gene expression levels in SubtiExpress: dsdA
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	49 kDa, 5.55
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	coaA, yqjQ
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes

The gene

Basic information

• Locus tag: BSU23770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-serine = pyruvate + NH₃ (according to Swiss-Prot)

• Protein family: DsdA subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54555

• KEGG entry: [3]

• E.C. number: 4.3.1.18

Expression and regulation

• Operon: yqjP-yqjQ-dsdA-coaA-yqjT (according to DBTBS)

• Expression browser: dsdA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Parsot
Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase.
EMBO J: 1986, 5(11);3013-9
[PubMed:3098560] [WorldCat.org] [DOI] (P p)