YncF

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  • Description: dUTP diphosphatase

Gene name yncF
Synonyms
Essential no
Product dUTP diphosphatase
Function nucleotide metabolism
Gene expression levels in SubtiExpress: yncF
MW, pI 16 kDa, 5.098
Gene length, protein length 432 bp, 144 aa
Immediate neighbours yncE, cotU
Sequences Protein DNA Advanced_DNA
Genetic context
YncF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YncF expression.png















Categories containing this gene/protein

nucleotide metabolism/ other

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17660

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YosS

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2XCD; 2XCE (complex with dUpnhpp)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Javier García-Nafría, Lynn Burchell, Mine Takezawa, Neil J Rzechorzek, Mark J Fogg, Keith S Wilson
The structure of the genomic Bacillus subtilis dUTPase: novel features in the Phe-lid.
Acta Crystallogr D Biol Crystallogr: 2010, 66(Pt 9);953-61
[PubMed:20823546] [WorldCat.org] [DOI] (I p)

Gui Lan Li, Juan Wang, Lan Fen Li, Xiao Dong Su
Crystallization and preliminary X-ray analysis of three dUTPases from Gram-positive bacteria.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2009, 65(Pt 4);339-42
[PubMed:19342774] [WorldCat.org] [DOI] (I p)