YlaM

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  • Description: glutaminase, high affinity for glutamine

Gene name ylaM
Synonyms
Essential no
Product glutaminase
Function glutamine degradation
Gene expression levels in SubtiExpress: ylaM
MW, pI 33 kDa, 5.676
Gene length, protein length 927 bp, 309 aa
Immediate neighbours ylaL, ylaN
Sequences Protein DNA Advanced_DNA
Genetic context
YlaM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlaM expression.png
























Categories containing this gene/protein

utilization of amino acids, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14830

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamine + H2O = L-glutamate + NH3 (according to Swiss-Prot)
  • Protein family: glutaminase family (according to Swiss-Prot)
  • Paralogous protein(s): GlsA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Greg Brown, Alex Singer, Michael Proudfoot, Tatiana Skarina, Youngchang Kim, Changsoo Chang, Irina Dementieva, Ekaterina Kuznetsova, Claudio F Gonzalez, Andrzej Joachimiak, Alexei Savchenko, Alexander F Yakunin
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
Biochemistry: 2008, 47(21);5724-35
[PubMed:18459799] [WorldCat.org] [DOI] (I p)