YkcC

• Description: similar to dolichol phosphate mannose synthase
  
  

Gene name	ykcC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ykcC
MW, pI	37 kDa, 8.011
Gene length, protein length	969 bp, 323 aa
Immediate neighbours	ykcB, htrA
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

membrane proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

YclJ regulon, YrkP regulon

The gene

Basic information

• Locus tag: BSU12890

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GtrB subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YkcC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed

• Localization:
  • cell membrane (heterogeneous) PubMed

Database entries

• Structure:

• UniProt: O34319

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ykcB-ykcC PubMed

• Expression browser: ykcC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YclJ: transcription activation PubMed
  • YrkP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Taku Ohsawa, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP.
Biosci Biotechnol Biochem: 2008, 72(1);186-96
[PubMed:18175906] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)